Surgical techniques and drilling parameters, such as rotational speed and feed-rate, have been shown to affect dental implant stability. Although thermally induced bone damage, caused during the drilling process, have been widely investigated to date, there is a dearth of knowledge regarding the mechanical effects of the drilling process on the dental implant stability. This study aimed at discovering the relation between drilling rotational speed (ω) & feed-rate (FR) and the dental implant (DI) stability, through in-vivo and ex-vivo investigations.